Aim of this module
This module will provide the trainee with the practical application of knowledge and skills relating to a range of immunological conditions, including immunodeficiencies, hypersensitivities and allergies and haematological malignancies. This module will provide the trainee with knowledge and understanding of the scientific basis of organ transplantation. They will understand the clinical preparation of patients for organ transplantation and the principles and practice of immunogenetics. They will become familiar with methods that support transplantation and gain experience of the interpretation of patient results in a variety of clinical settings. The trainee should be based in or spend extended time in a histocompatibility and immunogenetics department.
|Number||Work-based learning outcome||Title||Knowledge|
Select the appropriate immunological assay to investigate whether the immune system of the patient is immunocompetent or immunodeficient and have the laboratory skills to undertake at least two of the following laboratory analyses:
Interpret immunological data in the light of clinical details on patients with primary immunodeficiency including:
Select the appropriate immunological assay to investigate whether the immune system of the patient is producing an allergic response.
Interpret allergy test data in the light of clinical details and on patients with a range of common allergies including:
Select the appropriate immunological assay to investigate the immune system of patients with haematological malignancies such as:
Interpret data from immunological investigations, such as:
Work in partnership with other clinical specialisms in the investigation of a range of immunological conditions and, where appropriate, with service users and support staff.
Communicate effectively with the healthcare team recognising and responding appropriately to situations where it is necessary to share information to safeguard service users or the wider public.
|You must complete|
|2 Case-based discussion(s)|
|2 of the following DOPS / OCEs|
|Perform a test to measure IgE to an allergen||DOPS|
|Perform the test to determine total IgE levels in the serum of a patient||DOPS|
|Prepare DNA from a patient with a suspected haematological malignancy.||DOPS|
|Perform flow cytometric immunophenotyping on a patient following bone marrow reconstitution to determine whether lymphocyte subsets are returning.||DOPS|
|Perform analysis of a patients serum to determine levels of immunoglobulins IgG, IgM IgA||DOPS|
|Perform the assay to determine the level of anti-tetanus Or anti-pneumococcus Or anti-Hib IgG antibodies in a patient serum sample||DOPS|
|Perform the flow cytometric assay to determine the number of CD4 T cells||DOPS|
|Perform the assay to determine the C3 and C4 levels in a patient sample||DOPS|
|Undertake a skin prick test on a patient and explain to the patient how it is used by the lab||OCE|
|Observe a patch test on a patient and explain to the patient how it is used||OCE|
|Take a patient history for a patient with a suspected allergic reaction.||OCE|
|Attend an adult haematology clinic where haematological patients with myeloma may or may not have secondary immunodeficency and specifically note the types of laboratory assays that may be requested to assist in their management||OCE|
|Attend a paediatric haematology clinic where haematological patients with acute leukaemias will be assessed and specifically note the types of laboratory assays that may be requested to assist in their management||OCE|
|Take a history where the patient is suspected of having an immunodeficiency disorder||OCE|
|Attend an outpatient clinic within any discipline gastro rheumatology, dermatology, renal etc where the patient may have an immunological dysfunction as part of their disease||OCE|
The academic parts of this module will be detailed and communicated to you by your university. Please contact them if you have questions regarding this module and its assessments. The module titles in your MSc may not be exactly identical to the work-based modules shown in the e-portfolio. Your modules will be aligned, however, to ensure that your academic and work-based learning are complimentary.