Aim of this module
This module will provide the trainee with knowledge and understanding of the pathophysiology, clinical presentation and management of patients with haematological malignancies, transplantation and appropriate investigations. In the work-based module they will be expected to apply this knowledge as they learn to perform relevant laboratory methods and gain experience of the interpretation of patient results in a variety of clinical settings.
This module will provide the trainee with the practical application of knowledge and skills relating to the scientific principles of molecular techniques available for HLA typing and their applications for different clinical conditions.
|Number||Work-based learning outcome||Title||Knowledge|
Receive samples for HLA typing and enter onto laboratory IMS.
Extract and quantify DNA from samples according to local protocol.
Use local molecular based techniques in accordance with quality standards for intermediate resolution HLA typing.
Use local molecular based techniques in accordance with quality standards for High resolution typing.
Interpret data from HLA typing tests using current nomenclature and produce an HLA typing report for clinical colleagues.
Produce an interpretive genotyping report for a patient referred for disease association and pharmacogenetic reactions.
Work in partnership with other clinical specialisms in the investigation of disease association and pharmacogenetics and patients referred for transplantation and, where appropriate with service users and support staff.
Communicate effectively with the healthcare team recognising and responding appropriately to situations where it is necessary to share information to safeguard service users or the wider public.
|You must complete|
|2 Case-based discussion(s)|
|2 of the following DOPS / OCEs|
|Prepare a blood sample for molecular HLA testing||DOPS|
|Quantify and assess DNA samples for purity||DOPS|
|Perform HLA typing using local molecular methods||DOPS|
|Prepare an interpretive HLA report||DOPS|
|Perform tests for a patient referred for disease association or pharmacogenetic reactions||DOPS|
|Attend a multidisciplinary review meeting at which laboratory results are presented and describe to colleagues what they mean.||OCE|
|Take a patient history||OCE|
The academic parts of this module will be detailed and communicated to you by your university. Please contact them if you have questions regarding this module and its assessments. The module titles in your MSc may not be exactly identical to the work-based modules shown in the e-portfolio. Your modules will be aligned, however, to ensure that your academic and work-based learning are complimentary.
Current concepts on the aetiology, pathogenesis and molecular mechanisms involved in: