Aim of this module
These modules provide the trainees in Clinical Immunology and Histocompatibility and Immunogenetics with the knowledge that underpins the specialist modules in Clinical Immunology, and provide trainees with the knowledge and understanding that underpins and is applied to work-based learning.
This module will provide the trainee with knowledge, understanding and clinical significance of immunity as applied to infection and cancer. The trainee will become familiar with methods and strategies to investigate immunity and gain experience of the interpretation of patient results in a variety of clinical settings.
|Number||Work-based learning outcome||Title||Knowledge|
Select the appropriate immunological assay to investigate the status of the immune system in protecting the patient against a range of bacteria, viruses and fungi.
Apply methods to specified quality standards for all the following investigations:
Interpret immunological data in light of clinical details and be aware of the process of authorising written reports on patients with a variety of common infections, prior to and during therapy, including all of the following:
Identify cases requiring urgent intervention and be able to suggest what clinical advice on follow-up and/or further management could be offered.
Identify relevant clinical investigations from other disciplines that will impact on the interpretation of the immunological investigation.
|You must complete|
|2 Case-based discussion(s)|
|2 of the following DOPS / OCEs|
|Perform analysis of patients serum to determine level of IgG antibody to tetanus||DOPS|
|Perform analysis of patients serum to determine level of IgG antibody to haemophilius influenza||DOPS|
|Perform analysis of a patients serum to determine level of IgG antibody to pneumococcal polysaccharides||DOPS|
|Perform analysis of a patients serum to determine level of IgG antibody to individual polysaccharide serotypes of pneumococcus||DOPS|
|Perform analysis of a patients serum to determine level of IgG antibody to different fungal organisms||DOPS|
|Perform the assay either by flow or by NBT to assess if neutrophils are functioning||DOPS|
|Perform the assay to determine the C3 and C4 levels in a patient sample||DOPS|
|Perform the C100 or C50 assay to see if the classical pathway of complement is working in a patient||DOPS|
|Perform the AP50 AP100 assay to see if the alternative pathway of complement is working in a patient||DOPS|
|Perform TCR v beta analysis||DOPS|
|Take a history where the patient is suspected of having an immunodeficiency disorder specifically ask about bacterial and other infections||OCE|
|Where the patient is suspected of having an immunodeficiency disorder specifically observe the blood being taken for specific antibody assays to infectious agents||OCE|
|Where the patient is suspected of having an immunodeficiency disorder specifically observe if the patient is being given a test immunisation and note when the patient will have to return to have blood taken to assess the immune response to the vaccine||OCE|
|Attend an infectious paediatric clinic observe the history taking of a child with a history of infection and take a patient history on a volunteer||OCE|
|Attend an adult haematology clinic where haematological patients may have secondary immunodeficency and specifically note the types of infections they may have||OCE|
|Obtain a patient history from a normal volunteer or typical patient referred to your service and present the findings to a colleague or peer||OCE|
The academic parts of this module will be detailed and communicated to you by your university. Please contact them if you have questions regarding this module and its assessments. The module titles in your MSc may not be exactly identical to the work-based modules shown in the e-portfolio. Your modules will be aligned, however, to ensure that your academic and work-based learning are complimentary.