Embryology (SLS324)

10 credits

Aim of this module

This module will provide the trainee with the knowledge and understanding of the development and assessment of human pre-implantation embryos. They will gain experience of grading and assessing embryos and of interpreting the outcomes of assisted reproductive technology.

  1. Perform oocyte and embryo morphology assessments.
  2. Perform embryo transfer.
  3. Assess, interpret and report embryology results.
Number Work-based learning outcome Title Knowledge
1 1

Grade embryos both at the cleavage stage and the blastocyst stage.

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2 1,3

Accurately record embryo grading and outcome.

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3 1,2,3

Label, identify and witness embryos for use in embryo transfer.

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4 2

Use procedures and workstations to maintain embryo viability during embryo transfer.

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5 1,3

Dispose of unused embryos.

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6 1,3

Make clinical decisions regarding the number of embryos to be transferred.

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7 1,3

Communicate number of embryos to be transferred to patients.

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You must complete
2 Case-based discussion(s)
2 of the following DOPS / OCEs
Assessment Title Type
Carry out an embryo transfer DOPS
Grade and record embryo quality at different stages of development DOPS
Select embryos for transfer DOPS
Assess clinical presentation and cycle details to recommend the number of embryos to transfer DOPS
Dispose of embryos using appropriate witnessing DOPS
Discuss the number of embryos to be replaced with a patient including the implications and risks to the cycle outcome OCE
Discuss embryo development and quality with a patient and the implications for their treatment cycle OCE
Discuss embryo quality and the implications for cryopreservation with a patient OCE

Important information

The academic parts of this module will be detailed and communicated to you by your university. Please contact them if you have questions regarding this module and its assessments. The module titles in your MSc may not be exactly identical to the work-based modules shown in the e-portfolio. Your modules will be aligned, however, to ensure that your academic and work-based learning are complimentary.

Learning Outcomes

  1. Explain the cellular and molecular development of the human pre- implantation embryo.
  2. Describe relevant techniques for oocyte and embryo morphological assessments.
  3. Describe and evaluate the relevant technique for the process of embryo transfer.
  4. Discuss implantation and endometrial function.

Indicative Content

  • Human embryonic development and differentiation at all stages of the pre- implantation embryo
  • Genetic regulation of early embryonic development, including maternal and embryonic gene activity
  • Cellular and molecular aspects of embryo development
  • Chromosomal abnormalities, including meiotic origins and causes of monosomy and trisomy
  • Process of implantation and endometrial function
  • Grading methodologies from oocyte to blastocyst stage, assessment at all preimplantation stages
  • Identification of damaged, non-viable or abnormal gametes, zygotes or embryos
  • Assessment of gametes and embryos for intended use and implications for direct patient treatment
  • Handling and manipulation of embryos, including preparation of embryos and process of embryo transfer
  • Reporting outcomes of ART procedures