Aim of this module
This module will provide the trainee with the knowledge and understanding of paternal risk and heritability including the role of genetics, epigenetics, genomics, clinical bioinformatics and personalised medicine. Quality assurance, governance, ethical, legal and social implications of genetic and genomic testing will be explored. Clear understanding should be gained of the role that genetics and epigenetics may have in child health and considerations this gives in provision of fertility treatment approaches or guiding patients considering natural conception. Trainees should gain insight into patient and donor perspectives in these processes.
|You must complete|
|2 Case-based discussion(s)|
|2 of the following DOPS / OCEs|
|Take a clinical history from a couple, including relevant genetic and heritable risks.||DOPS|
|Gather a history from a potential sperm donor||DOPS|
|Obtain consent from a patient / donor for further genetic testing, taking into account best practice guidelines related to genetic tests.||DOPS|
|Evaluate and discuss the risks of consanguinity in reproduction.||OCE|
|Evaluate the potential effects on a sperm donor / patient of unexpected findings about their genetics. Discuss with your team how these relate to best practice locally.||OCE|
|Evaluate the risk, ethical and social factors related to ART for couples offspring where the man has known Y-deletions, but still some spermatogenesis and discuss with colleagues.||OCE|
|Evaluate the risk of different heritable conditions in different potential donors / patients, including a background assessment of how ethnic background may affect screening for these. Discuss with relevant team.||OCE|
|Evaluate options for couples seeking ART with a known genetic risk, including but not limited to from a regulatory and ethical perspective. Justify your summary recommendations to your team.||OCE|
The academic parts of this module will be detailed and communicated to you by your university. Please contact them if you have questions regarding this module and its assessments. The module titles in your MSc may not be exactly identical to the work-based modules shown in the e-portfolio. Your modules will be aligned, however, to ensure that your academic and work-based learning are complimentary.